aesthetic surgery
combining caha and microfocused ultrasound for skin tightening
Authors: Yutskovskaya YA, Kogan EA
combination of calcium hydroxylapatite diluted with normal saline andmicrofocused ultrasound with visualisation for skin tightening
background & objectives
Treatment options for the correction of age-related changes in skin include the use of energy-based devices and dermal fillers. In this study, we evaluate the clinical efficacy and tolerability of microfocused ultrasound with visualisation (MFU-V) and injectable calcium hydroxylapatite (CaHA) filler diluted with normal saline, for the correction of age-related changes and to assess patients' satisfaction with this combination therapy.
materials & methods
This was a randomised, split-face, comparative clinical study and immunohistochemical analysis in 20 subjects with indications for lower face, neck and décolleté lifting. Over five visits, CaHA diluted with normal saline (1:2) was injected subdermally in the lower third of the face, neck and décolleté, and lower abdominal quadrant. MFU-V was performed on the lower third of the face, neck, and décolleté, and the right lower abdominal quadrant.
results
Upon baseline examination, the age-related changes were quantified as follows: marionette lines score 2.47 ± 0.8, jawline contour score 2.2 ± 0.7 and neck score 2.1 ± 0.7 points; and after 15 months, they changed to 1.8 ± 0.7 (P≤0.00003), 1.89 ± 0.56 (P≤0.005), and 1.7 ± 0.6 (P≤0.005) points, respectively. The procedures were well tolerated, and subject satisfaction was high.
conclusion
The injections of CaHA in combination with MFU-V treatment stimulated neo-angiogenesis, led to the increased synthetic activity of cells, a marked increase in collagen and elastin fibres, and remodelling of both the superficial and deep layers of the dermis. An improvement in the severity of age-related changes was observed in all areas studied.
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