In this video, Dr. Jani van Loghem demonstrates the full workflow of an autologous exosome system, from blood collection through to a concentrate that is ready for treatment. He talks through each stage of the closed ultrafiltration process, explaining how a membrane cut-off retains the components above a defined molecular weight and how mechanical stimulation of the platelets promotes exosome release. Practical points on handling, timing and volume reduction are covered throughout, giving a clear and reproducible overview for practitioners introducing autologous exosome therapy into their clinic.